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Index/Topics/PSMA Expression

PSMA Expression

PSMA expression increases with higher grade and castration resistance

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Jan 21, 2026

What molecular signatures distinguish low‑PSA, high‑grade prostate cancers from PSA‑secreting tumors?

that paradoxically secrete little PSA are molecularly distinct from conventional PSA‑secreting tumors: they show reduced androgen receptor (AR) output and PSA expression, enrichment for transcriptiona...

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