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PSMA PET/CT for Prostate Cancer

The use of PSMA PET/CT in detecting recurrent prostate cancer and its impact on salvage radiotherapy plans.

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Jan 18, 2026
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Can elevated PSA levels after prostate surgery indicate cancer recurrence?

Yes — a rise in prostate‑specific antigen (PSA) after radical prostatectomy is commonly the earliest laboratory sign that prostate cancer may have recurred, but interpretation depends on timing, magni...

Jan 15, 2026
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What is the comparative performance of mpMRI versus PSMA PET/CT for localizing prostate cancer recurrence in the prostatectomy bed?

For localizing prostate cancer recurrence specifically within the prostatectomy bed, multiparametric MRI (mpMRI) remains the favored tool for high-resolution anatomic localization while PSMA PET/CT ad...

Jan 19, 2026

How do PSA level and PSA doubling time influence the sensitivity of mpMRI for detecting local recurrence after prostatectomy?

Multiparametric MRI (mpMRI) is a powerful tool for localizing recurrence after radical prostatectomy, but its sensitivity is strongly influenced by the absolute PSA at biochemical recurrence and by PS...

Jan 13, 2026

How does PSMA PET imaging change salvage radiotherapy planning and outcomes in early PSA recurrence?

PSMA PET/CT markedly improves detection of recurrent prostate cancer at very low PSA levels and changes salvage radiotherapy (sRT) plans in a majority of cases, but definitive evidence that PET-guided...