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Index/Topics/Randomized Clinical Trials of Berberine

Randomized Clinical Trials of Berberine

Randomized clinical trials examining the efficacy and safety of berberine in metabolic disorders.

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Jan 14, 2026
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Berberine efficacy

Clinical trials and multiple meta-analyses show that berberine and some engineered berberine salts improve key metabolic outcomes—fasting glucose, HbA1c, insulin resistance markers, and lipid profiles...

Jan 6, 2026

What randomized clinical trial evidence exists for berberine’s side effects and incidence rates in metabolic studies?

Randomized clinical trials (RCTs) of berberine in metabolic disorders consistently report a tolerability pattern dominated by mild gastrointestinal symptoms, with one early trial documenting transient...

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