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Rectal microbiome alteration

The alteration of the rectal microbiome due to frequent douching, including changes in microbial composition and the potential for increased susceptibility to infections.

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Jan 30, 2026
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How do different douching solutions (water, saline, soapy, hyperosmotic) compare in their effects on rectal mucosa and microbiome?

Rectal douching solutions vary in how they interact with the fragile single‑layer rectal epithelium and the resident microbiome: plain water and soapy water commonly used by people are linked to epith...

Jan 26, 2026
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How does rectal douching frequency affect the rectal microbiome over time?

is repeatedly associated in the literature with measurable changes to the rectal mucosa and with shifts in microbial composition that plausibly increase susceptibility to infections; higher douching f...