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Index/Topics/Semaglutide Efficacy

Semaglutide Efficacy

Comparison of semaglutide with other GLP-1RAs and SGLT2 inhibitors in terms of efficacy for weight loss and glycaemic control

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3 results
Jan 13, 2026

What are the head‑to‑head A1C and weight results for semaglutide versus other GLP‑1RAs and SGLT2 inhibitors?

Randomized trials and pooled analyses show semaglutide delivers larger average reductions in HbA1c and body weight than many other GLP‑1 receptor agonists (GLP‑1RAs), with head‑to‑head meta‑analysis f...

Jan 12, 2026

What are the clinically proven differences between GLP‑1 prescription drugs and over‑the‑counter weight‑loss supplements?

Prescription GLP‑1 receptor agonists are clinically tested, regulated drugs that mimic the GLP‑1 hormone to slow gastric emptying, reduce appetite and produce substantial, trial-proven weight loss, wh...

Jan 9, 2026

How does tirzepatide compare to other GLP‑1 drugs for weight loss in clinical trials?

Tirzepatide — a dual GIP and GLP‑1 receptor agonist — produces larger average weight losses in randomized trials than single‑receptor GLP‑1 drugs such as semaglutide and liraglutide, with dose‑depende...

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