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Index/Topics/Silodosin Ejaculatory Dysfunction Risk

Silodosin Ejaculatory Dysfunction Risk

Silodosin causes the highest rates of ejaculatory dysfunction among α1-blockers.

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Jan 27, 2026
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What are the ejaculatory side‑effect rates for other α1‑blockers (silodosin, alfuzosin, doxazosin) compared with tamsulosin?

causes the highest rates of ejaculatory dysfunction (EjD) among α1‑blockers, with trials and meta‑analyses reporting point estimates in the low‑to‑high‑teens and some series up to ~22–28%; pooled anal...

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