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The effect of sodium bicarbonate on endothelial function in patients with chronic kidney disease (CKD), including the results of various clinical trials and the proposed mechanisms for its beneficial effect.
Two randomized clinical trials directly tested oral sodium bicarbonate for effects on endothelial function measured by brachial artery flow‑mediated dilation (FMD): a small 2018 pilot randomized cross...
Randomized trials and meta-analyses identify recurring signals that N‑acetylcysteine (NAC) may help when given orally, at higher cumulative doses for respiratory disease, as a pre‑procedure pretreatme...
Three types of human studies have tested oral sodium bicarbonate with endpoints tied to endothelial function or blood flow: small randomized trials (including a 2018 pilot crossover trial), short sing...