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Index/Topics/St. John's wort's effect on CYP3A4

St. John's wort's effect on CYP3A4

St. John's wort's induction of CYP3A4

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Jan 16, 2026
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Which prescription drugs metabolized by CYP3A4 have documented interactions with herbal supplements?

St. John’s wort, grapefruit (juice), and a range of polyphenol-rich herbal supplements have documented, clinically significant interactions with prescription drugs that are substrates of CYP3A4, alter...

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