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A disease caused by parasitic worms and the use of ivermectin in its treatment.
High‑dose ivermectin studies in humans and pharmacovigilance analyses document a spectrum of neurologic events—from common, mild symptoms such as dizziness and somnolence observed in trials to rare bu...
is a well-established antiparasitic with robust evidence and regulatory approval for treating intestinal strongyloidiasis and substantial, though more variable, evidence supporting its use for scabies...
Ivermectin is largely metabolized by the liver and excreted in feces, with minimal unchanged renal excretion, so routine dose adjustment for chronic kidney disease (CKD) is commonly not required; neve...
Clinical guidelines converge on simple, highly effective single‑dose oral regimens for intestinal Ascaris and on specific, non‑praziquantel therapy for fascioliasis, while management of human echinoco...
Clinicians must identify or exclude high Loa loa microfilaremia before giving ivermectin in endemic areas because serious adverse events—including encephalopathy and death—are tightly linked to high c...
Ivermectin carries known side effects when used in humans — ranging from common, transient reactions (itching, fever, headache) to rare but serious neurological events — and is not a standard, proven ...