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Index/Topics/Tirzepatide Efficacy

Tirzepatide Efficacy

Efficacy of tirzepatide for weight loss and glycaemic control

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2 results
Jan 13, 2026

What are the head‑to‑head A1C and weight results for semaglutide versus other GLP‑1RAs and SGLT2 inhibitors?

Randomized trials and pooled analyses show semaglutide delivers larger average reductions in HbA1c and body weight than many other GLP‑1 receptor agonists (GLP‑1RAs), with head‑to‑head meta‑analysis f...

Jan 9, 2026

How does tirzepatide compare to other GLP‑1 drugs for weight loss in clinical trials?

Tirzepatide — a dual GIP and GLP‑1 receptor agonist — produces larger average weight losses in randomized trials than single‑receptor GLP‑1 drugs such as semaglutide and liraglutide, with dose‑depende...

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