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Index/Topics/Topical Alprostadil Creams

Topical Alprostadil Creams

Use of topical alprostadil creams as an alternative for erectile dysfunction treatment

Fact-Checks

4 results
Feb 6, 2026

How do vacuum erection devices compare to oral ED medications in randomized trials?

Randomized trials and major reviews show that vacuum erection devices () reliably produce adequate erections for many men—approximately 70% in pooled reports of device trials—and are especially useful...

Feb 6, 2026

When should someone see a doctor for persistent erectile problems?

Persistent erectile problems — defined in practice as repeated difficulty achieving or maintaining an erection sufficient for sex — warrant medical attention because most cases have a physical compone...

Feb 4, 2026

What clinical steps should be taken to evaluate low testosterone or erectile dysfunction before using OTC supplements?

A safe, evidence-based evaluation for suspected low testosterone or (ED) requires a , targeted laboratory testing with proper timing and assay awareness, and exclusion of reversible medical, psycholog...

Jan 31, 2026

How effective are topical ED creams compared with prescription PDE‑5 inhibitors in clinical trials?

—most robustly studied in the form of alprostadil formulations—have demonstrated clinically meaningful benefit in randomized trials and real‑world use, particularly for men who cannot take ; however, ...

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