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Index/Topics/Topical Vasodilators

Topical Vasodilators

Topical vasodilators, such as nifedipine and nitrates, for treating anal fissures

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1 result
Feb 1, 2026

Which topical and pharmacologic treatments (e.g., nitroglycerin, calcium‑channel blockers) are evidence‑based for anal fissure healing after sexual trauma?

Topical vasodilators and agents that reduce internal anal sphincter tone—most commonly (eg, nifedipine) and topical nitrates—have the strongest non‑surgical evidence for promoting healing, and is an e...

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