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Index/Topics/Vardenafil Efficacy

Vardenafil Efficacy

Efficacy and potency of vardenafil compared to other PDE5 inhibitors

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3 results
Jan 14, 2026
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Are there differences in side effect profiles between sildenafil, tadalafil, and vardenafil?

Sildenafil, tadalafil and vardenafil share a broadly similar adverse‑effect footprint — headaches, flushing, dyspepsia and nasal congestion are the common themes — but they differ in pharmacokinetics ...

Feb 2, 2026

How do PDE5 inhibitors differ in onset and duration of action and which is best for on‑demand use?

differ primarily in pharmacokinetics—how quickly they reach effective blood levels (onset) and how long they remain active (duration)—and those differences drive which drug is optimal for “on‑demand” ...

Jan 14, 2026

Are there patient characteristics that predict better tolerability of one PDE5 inhibitor over another?

Yes — some patient characteristics can guide which PDE5 inhibitor is likely to be better tolerated, but the signal is modest: pharmacokinetic differences (half‑life, food interactions), cardiovascular...

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