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Index/Topics/Virus neutralization tests

Virus neutralization tests

Measuring functional antibodies that block spike-ACE2 interactions

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Jan 8, 2026

What laboratory methods are used to detect spike protein and how do they differ in sensitivity and specificity?

Laboratory detection of the SARS‑CoV‑2 spike protein and spike‑specific antibodies uses two broad approaches: direct antigen detection (immunoassays, lateral flow, biosensors) and serological assays t...

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