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Index/Topics/Weight Management Medications

Weight Management Medications

Different weight management medications, including semaglutide and tirzepatide, and their efficacy in preventing weight regain.

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Jan 17, 2026

What strategies (tapering, combination drugs, or intensive behavioral programs) have been tested to prevent weight regain after stopping semaglutide?

Stopping semaglutide commonly triggers substantial weight regain: randomized trials and extensions show most people regain the majority of lost weight within a year to two years after drug withdrawal ...

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