Index/Topics/Berberine vs Metformin

Berberine vs Metformin

Comparing the effectiveness of berberine and metformin in treating type 2 diabetes

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Jan 14, 2026
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What randomized trials compare berberine or bitter melon directly with metformin in type 2 diabetes?

Randomized trials directly comparing berberine with metformin include a small 3-month pilot (Yin et al.) that randomized newly diagnosed type 2 diabetes patients to berberine or metformin and found co...

Jan 14, 2026
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What randomized controlled trials have compared herbal nutraceutical supplements versus metformin or placebo for lowering HbA1c, and what were their sample sizes and outcomes?

Randomized controlled trials (RCTs) have tested several herbal nutraceuticals—most extensively berberine—and a handful of multiherb formulas against placebo and, less often, against metformin; the evi...

Jan 31, 2026
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What major clinical trials have tested cinnamon, berberine or fenugreek for type 2 diabetes and what were their results?

Multiple randomized controlled trials and meta-analyses have tested -vs-metformin">berberine, , and in people with prediabetes or type 2 diabetes; overall the literature shows signals of modest glycem...

Feb 6, 2026

What randomized controlled trials compare berberine directly to metformin for type 2 diabetes and what were their sample sizes and durations?

directly comparing berberine to metformin are few and small: the oft‑cited head‑to‑head pilot by randomized 36 newly diagnosed patients to for about three months and reported comparable glycemic reduc...

Jan 18, 2026

How does berberine compare with metformin for glycemic control in randomized trials?

Randomized trials and pooled analyses show that berberine produces meaningful short-term reductions in HbA1c, fasting plasma glucose (FPG) and postprandial glucose that are frequently similar in magni...