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The use of PDE-5 inhibitors in combination with VED therapy to improve subjective measures and compliance.
—also called vacuum erection devices (VEDs)—are widely regarded by urologists and medical references as a safe, noninvasive, and effective short‑to‑medium term option for achieving erections when oral...
Choosing a vacuum erection device () requires matching clinical need, device features and realistic expectations: a VED uses negative pressure to draw blood into the penis and a constriction ring can ...
Phosphodiesterase type 5 inhibitors () — oral drugs such as sildenafil, tadalafil and avanafil — are the established, first-line, evidence-based treatments for because they reliably improve erections ...
Vacuum erection devices (VEDs) are an effective, noninvasive option for many men with erectile dysfunction (ED), but there are clear clinical situations in which they are discouraged or require extrem...
Herbal remedies such as red ginseng, yohimbe/yohimbine and horny goat weed are widely marketed for erectile dysfunction (ED) and have some biological rationale and mixed clinical signals, but the clin...
Randomized human trials show that early use of vacuum erectile devices (VEDs) after does not reliably restore spontaneous erectile function but does have consistent, clinically meaningful effects in p...
Randomized trials that directly compare one vacuum erection device (VED) against another — true head‑to‑head device trials — do not appear in the provided literature; the randomized evidence cataloged...
Concerns about commonly cause distress and can contribute to sexual dysfunction, but most evidence-based treatments target function rather than permanent size change: first-line options include counse...
Prescription organic nitrates such as nitroglycerin interact dangerously with phosphodiesterase‑5 (PDE5) inhibitors used for because both drug classes increase cyclic GMP (cGMP) in vascular smooth mus...
usually starts with addressing and — exercise, weight loss, , and diet changes reliably improve erections in many men . When lifestyle measures are insufficient, a range of evidence‑based options exis...
Clinical human research directly testing (ED) is extremely limited: one randomized clinical trial tested melatonin versus zolpidem and placebo in and found no improvement in erectile function scores, ...
Penile prostheses mechanically restore rigidity for penetrative sex but do not re-create the neurovascular mechanisms that produce natural erections, and most guidelines and studies emphasize that imp...
Peer‑reviewed clinical studies of vacuum erection devices (VEDs) as penile rehabilitation after radical prostatectomy include small randomized controlled trials, prospective controlled trials, pilot p...
Yes — some patient characteristics can guide which PDE5 inhibitor is likely to be better tolerated, but the signal is modest: pharmacokinetic differences (half‑life, food interactions), cardiovascular...
Since 2010 dozens of sexual‑enhancement products marketed as “natural” dietary supplements have been recalled or publicly warned about after laboratory testing found undeclared prescription drugs—most...
Clinical research shows both L-arginine and L-citrulline can modestly improve erectile function in some men, particularly those with mild to moderate or vasculogenic ED, but evidence is stronger and m...
Clinical trial evidence supports some benefit of L‑arginine for mild-to-moderate erectile dysfunction (ED), both as a single high‑dose agent and in combination products—yet results are mixed across st...
Penile girth (circumference) shows little consistent association with objective erectile dysfunction (ED) in clinical research: measured girth often does not differ significantly between men with and ...