Index/Topics/Randomized Controlled Trials

Randomized Controlled Trials

The use of randomized controlled trials to compare the effectiveness of berberine and metformin

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22 results
Jan 29, 2026
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How have scientific watchdogs and journals evaluated clinical claims about ivermectin, fenbendazole, and mebendazole in cancer treatment?

Scientific watchdogs and mainstream journals portray as biologically plausible but clinically unproven cancer therapies: robust preclinical data exist showing antiproliferative mechanisms, while case ...

Jan 16, 2026
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What does randomized evidence say about Genicular Artery Embolization versus sham or standard care for knee osteoarthritis?

Randomized evidence on genicular artery embolization (GAE) for knee osteoarthritis shows short-term pain reductions in some trials versus sham procedures, especially on visual analogue scale (VAS) mea...

Jan 28, 2026
Most Viewed

Which probiotic strains have randomized controlled trials for IBS and what doses were used?

(RCTs) have tested a range of single probiotic strains and multi‑strain formulations for irritable bowel syndrome (IBS), with several strains showing outcome‑specific benefits but wide heterogeneity i...

Jan 23, 2026

How can consumers verify whether a supplement’s clinical claims are supported by peer‑reviewed trials?

Consumers who want to verify a supplement’s should look for human (RCTs) that were published in , check that the studied product, dose and population match the marketed product, and confirm study qual...

Feb 6, 2026

What randomized controlled trials compare berberine directly to metformin for type 2 diabetes and what were their sample sizes and durations?

directly comparing berberine to metformin are few and small: the oft‑cited head‑to‑head pilot by randomized 36 newly diagnosed patients to for about three months and reported comparable glycemic reduc...

Feb 4, 2026

Are there randomized controlled trials comparing aged garlic extract monotherapy to specific antihypertensive drug classes (ACE inhibitors, ARBs, CCBs, diuretics)?

Randomized controlled trials (RCTs have tested aged garlic extract (AGE) versus placebo and as an adjunct to antihypertensive therapy, but the peer‑reviewed sources provided do not document randomized...

Feb 1, 2026

what is the evidence for ivermectin and various supplements for fighting metastatic breast cancer?

Laboratory and animal studies show has measurable anticancer activity in breast cancer models—especially (TNBC)—and can “convert cold tumors hot,” providing a mechanistic rationale for combining it wi...

Jan 29, 2026

How can I trace the original research behind a health claim and judge its quality?

Tracing the original research behind a requires a methodical "trace and test" approach: find the primary studies cited, assess their design and execution, and evaluate the totality of evidence using e...

Jan 28, 2026

What randomized controlled trials exist testing Manuka honey for glycemic control in humans?

A small and fragmented human trial record suggests investigators have planned or run randomized trials involving , but there is no robust body of (RCTs) that directly tests mānuka honey’s effect on gl...

Jan 22, 2026

Which clinical sources should patients consult to evaluate claims about new diabetes treatments?

A practical shortlist of clinical sources patients should consult to evaluate claims about new includes high-quality and network meta-analyses, catalogued in major databases, from professional societi...

Jan 19, 2026

Are there peer‑reviewed studies on gelatin or collagen supplements and appetite control or weight loss?

Yes — there are peer‑reviewed human studies and randomized trials testing gelatin or collagen (often labelled collagen peptides or hydrolysed gelatin) for effects on appetite regulation and body compo...

Jan 18, 2026

What randomized evidence exists on cardiovascular outcomes after planned discontinuation of GLP‑1 therapy?

Randomized trial data directly assessing cardiovascular outcomes after a planned, protocolized discontinuation of GLP‑1 receptor agonists are scarce: most randomized controlled trials (RCTs) report ca...

Jan 17, 2026

Which randomized trials have measured intramuscular NAD+ directly after NMN or NR supplementation?

Randomized trials of NMN and NR in humans have repeatedly measured blood and peripheral-blood-cell NAD+ metabolites, urine excretion products, and downstream muscle function or protein markers, but th...

Jan 16, 2026

What randomized controlled trials compare gelatin or collagen supplements directly with whey or casein for short‑term appetite and energy intake?

Randomized controlled trials directly comparing gelatin or collagen with whey or casein for short‑term appetite and energy intake are limited but informative: a 2009 randomized breakfast study found g...

Jan 16, 2026

What large randomized controlled trials of hydrogen-rich water are currently registered or recruiting?

Large, definitive randomized controlled trials (RCTs testing hydrogen‑rich water (HRW) are scarce: most human trials to date are small, pilot or mid‑sized RCTs (tens of participants), with systematic ...

Jan 14, 2026

Has any peer‑reviewed randomized controlled trial been published for MemoBlast or Memory Blast?

No peer‑reviewed randomized controlled trial (RCT) for the dietary supplement MemoBlast (also marketed as Memory Blast in some outlets) is documented in the provided reporting: consumer reviews note a...

Jan 12, 2026

What randomized clinical trials exist for cinnamon, chromium, and ginseng in type 2 diabetes management?

Randomized clinical trials (RCTs) testing cinnamon, chromium, and ginseng for type 2 diabetes (T2D) are numerous but heterogeneous: cinnamon has been evaluated in many small RCTs and several meta-anal...

Jan 11, 2026

How reliable are user testimonials and marketplace reviews for evaluating supplement efficacy?

User testimonials and marketplace reviews are poor substitutes for controlled scientific evidence when judging whether a supplement actually works: they are anecdotal, subject to placebo effects and s...

Jan 8, 2026

How do different types and dosages of honey compare to isocaloric sugar controls in human randomized trials?

Randomized human trials that directly compare honey to isocaloric sugar controls show a mixed picture: some trials and meta-analyses suggest modest cardiometabolic advantages for certain honey regimen...

Jan 8, 2026

Which green tea extract doses and formulations produced the largest clinically meaningful weight changes in long‑term RCTs?

High‑dose isolated EGCG (around 856.8 mg/day) and green tea catechin formulations combined with caffeine have produced the largest measurable changes in short‑to‑moderate duration randomized controlle...