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The use of testosterone replacement therapy to restore libido and improve erectile function after orchiectomy.
The most consistent and replicated neuroendocrine change after orgasm in women is an elevation in plasma prolactin that is orgasm-dependent and typically sustained for about an hour; other candidate h...
(KS, typically 47,XXY) is often associated with reduced penile length in childhood and adulthood-related hypogonadism that can limit unless treated with androgens . (AIS) — ranging from complete to pa...
Phosphodiesterase type 5 inhibitors (PDE5i) — oral drugs such as sildenafil — are the evidence‑based, guideline‑recommended first‑line pharmacologic treatment for most men with erectile dysfunction (E...
are best addressed with a mix of behavioral, psychological, relational, and device-based strategies rather than as purely a pharmacologic problem; most guidelines and reviews recommend , , behavioral ...
Removal of one testicle (unilateral orchiectomy) usually does not prevent because the remaining testicle typically maintains testosterone production and sexual function . Removal of both testicles (bi...
The best off‑the‑shelf supplements with the most consistent clinical support for modest increases in serum testosterone are ashwagandha and fenugreek, with vitamin D supplementation indicated when a d...
(HRT) that includes estrogens modestly improves aspects of sexual function after menopause—particularly lubrication, pain, and overall satisfaction—yet for most women it produces only small gains in d...
Evidence in the medical literature portrays a nuanced relationship: testosterone (T) affects libido and can improve erectile function in men with clinically low T, but large studies fail to show a dir...
Pelvic floor dysfunction alters the muscular, sensory, and autonomic scaffolding required for male orgasm, and its effects are amplified or mitigated by intertwined neurological and psychological fact...
Medical therapies that reliably and predictably increase semen volume in men over 50 are limited: treating identifiable medical causes—obstructive problems, prostate enlargement or medication effects—...
Current research shows two related threads: prostate structure and function change with age and these changes—plus treatments for prostate conditions—can influence libido, but the mechanisms are compl...
Testosterone drives penile growth during fetal development and puberty, but after physical maturity additional testosterone — whether prescribed TRT or over-the-counter boosters — does not meaningfull...
Dry orgasm is a symptom with multiple meanings—most commonly in men the experience of orgasm without ejaculate and in women the loss of lubrication and orgasmic response tied to vaginal atrophy—and ho...
Several medications can alter the usual coupling of orgasm and ejaculation—either by delaying or preventing semen emission while allowing the perceptual orgasm to occur, or by restoring orgasm when ej...